3-(3-Carboxy-4-hydroxy-phenyl)-L-alanine (m-Carboxy-L-tyrosine), a New Amino Acid Isolated from Seeds of Reseda odorata L.

Biosynthesis of 3-Carboxy-6,7-dihydroxy-l, 2,3,4-tetra- hydroisoquinoline and l-Methyl-3-carboxy-6,7-dihydroxy-l, 2,3,4- tetrahydroisoquinoline in a Callus Culture of Stizolobium hassjoo

dl-[/?-14C] 3,4-Dihydroxyphenylalanine (DOPA), [2-14C]pyruvate and [2-14C]acetate were ad­ ministered to a callus culture of S. hassjoo and incorporation of the radioactivity into 3-carboxy6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (I) and l-methyl-3-carboxy-6,7-dihydroxy-1,2,3,4tetrahydroisoquinoline (II) was examined. Incorporation of radioactivity from labelled DOPA into I and II, and from...

A M I C Acid 60 - L - Alanine 30 - L - Tyrosine 10 ( Gat ) by Craig

B lymphocytes and certain subpopulations of T lymphocytes respond to stimulation with antigen by synthesis and secretion of unique glycoproteins capable of binding the stimulating antigen. In the case of the B cell, these glycoproteins are the classic antibody molecules, which have been well characterized in terms of structure, function, and organization, both at the protein and nucleic acid le...

N-[(2S)-4-Chloro-2-(l-menthyloxy)-5-oxo-2,5-dihydro-3-furyl]-l-alanine

The title compound, C(17)H(26)ClNO(5), was prepared via a tandem asymmetric Michael addition-elimination reaction of (5S)-3,4-dichloro-5-(l-menth-yloxy)furan-2(5H)--one and l-alanine in the presence of potassium hydroxide. The five-membered furan-one ring is approximately planar while the six-membered menth-yloxy ring adopts a chair conformation. The crystal packing is stabilized by inter-molec...

Affinity labeling of alanine aminotransferase by 3-chloro-L-alanine.

The pyridoxal form of alanine aminotransferase from pig heart catalyzes the a,/? elimination reaction with 3chloro-L-alanine as the substrate to form equimolar amounts of pyruvate, ammonia, and chloride. The maximum rate of the a,/3 elimination reaction was 2.5 pmol/min/mg at pH 7.0 (25”(Z), approximately 0.5% that of the transamination reaction between L-alanine and 2-oxoglutarate. Time-depend...

Substituted l - dialkylaminomethyl - 3 - phenyl - 1 - naphthalenemethanols